Tissue-Specific, Tumor-Selective, Replication-Competent Adenovirus Vector for Cancer Gene Therapy

We have previously described two replication-competent adenovirus vectors, named KD1 and KD3, for potential use in cancer gene therapy. KD1 and KD3 have two small deletions in the E1A gene that restrict efficient replication of these vectors to human cancer cell lines. These vectors also have increa...

ver descrição completa

Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Doronin, Konstantin, Kuppuswamy, Mohan, Toth, Karoly, Tollefson, Ann E., Krajcsi, Peter, Krougliak, Valeri, Wold, William S. M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Gene Therapy
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114124/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11238857/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.7.3314-3324.2001
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!