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A unique amino acid of the Drosophila GABA receptor with influence on drug sensitivity by two mechanisms.

1. The Drosophila gene Rdl (resistance to dieldrin) encodes a GABA receptor. An alanine-to-serine mutation in this gene at residue 302 confers resistance to cyclodiene insecticides and picrotoxin. Patch clamp analysis of GABA receptors in cultured neurons from wild type and mutant Drosophila was und...

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Detalhes bibliográficos
Main Authors: Zhang, H G, ffrench-Constant, R H, Jackson, M B
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1155726/
https://ncbi.nlm.nih.gov/pubmed/7527461
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