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A deoxyribozyme that synthesizes 2′,5′-branched RNA with any branch-site nucleotide

RNA molecules with internal 2′,5′-branches are intermediates in RNA splicing, and branched RNAs have recently been proposed as retrotransposition intermediates. A broadly applicable in vitro synthetic route to branched RNA that does not require self-splicing introns or spliceosomes would substantial...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Pratico, Elizabeth D., Wang, Yangming, Silverman, Scott K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1153712/
https://ncbi.nlm.nih.gov/pubmed/15967808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki656
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