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Improved deoxyribozymes for synthesis of covalently branched DNA and RNA

A covalently branched nucleic acid can be synthesized by joining the 2′-hydroxyl of the branch-site ribonucleotide of a DNA or RNA strand to the activated 5′-phosphorus of a separate DNA or RNA strand. We have previously used deoxyribozymes to synthesize several types of branched nucleic acids for e...

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Detalhes bibliográficos
Main Authors: Lee, Christine S., Mui, Timothy P., Silverman, Scott K.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017605/
https://ncbi.nlm.nih.gov/pubmed/20739352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq753
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