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In vitro selection, characterization, and application of deoxyribozymes that cleave RNA
Over the last decade, many catalytically active DNA molecules (deoxyribozymes; DNA enzymes) have been identified by in vitro selection from random-sequence DNA pools. This article focuses on deoxyribozymes that cleave RNA substrates. The first DNA enzyme was reported in 1994 and cleaves an RNA linka...
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| Autor principal: | |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2005
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1283523/ https://ncbi.nlm.nih.gov/pubmed/16286368 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki930 |
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