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In vitro selection, characterization, and application of deoxyribozymes that cleave RNA

Over the last decade, many catalytically active DNA molecules (deoxyribozymes; DNA enzymes) have been identified by in vitro selection from random-sequence DNA pools. This article focuses on deoxyribozymes that cleave RNA substrates. The first DNA enzyme was reported in 1994 and cleaves an RNA linka...

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Autore principale: Silverman, Scott K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1283523/
https://ncbi.nlm.nih.gov/pubmed/16286368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki930
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