High affinity nucleic acid aptamers for streptavidin incorporated into bi-specific capture ligands

We have isolated 2′-Fluoro-substituted RNA aptamers that bind to streptavidin (SA) with an affinity around 7 ± 1.8 nM, comparable with that of recently described peptide aptamers. Binding to SA was not prevented by prior saturation with biotin, enabling nucleic acid aptamers to form useful ternary c...

詳細記述

書誌詳細

出版年:	Nucleic Acids Res
主要な著者:	Tahiri-Alaoui, Abdessamad, Frigotto, Laura, Manville, Nick, Ibrahim, Jamal, Romby, Pascale, James, William
フォーマット:	Artigo
言語:	Inglês
出版事項:	Oxford University Press 2002
主題:	NAR Methods Online
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC115299/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12000850/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/30.10.e45
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