High affinity nucleic acid aptamers for streptavidin incorporated into bi-specific capture ligands
We have isolated 2′-Fluoro-substituted RNA aptamers that bind to streptavidin (SA) with an affinity around 7 ± 1.8 nM, comparable with that of recently described peptide aptamers. Binding to SA was not prevented by prior saturation with biotin, enabling nucleic acid aptamers to form useful ternary c...
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| Yayımlandı: | Nucleic Acids Res |
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| Asıl Yazarlar: | , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Oxford University Press
2002
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC115299/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12000850/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/30.10.e45 |
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