High affinity nucleic acid aptamers for streptavidin incorporated into bi-specific capture ligands

We have isolated 2′-Fluoro-substituted RNA aptamers that bind to streptavidin (SA) with an affinity around 7 ± 1.8 nM, comparable with that of recently described peptide aptamers. Binding to SA was not prevented by prior saturation with biotin, enabling nucleic acid aptamers to form useful ternary c...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	Nucleic Acids Res
Päätekijät:	Tahiri-Alaoui, Abdessamad, Frigotto, Laura, Manville, Nick, Ibrahim, Jamal, Romby, Pascale, James, William
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Oxford University Press 2002
Aiheet:	NAR Methods Online
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC115299/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12000850/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/30.10.e45
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