טוען...
Small-molecule inhibition of proteasome and aggresome function induces synergistic antitumor activity in multiple myeloma
We have shown that the proteasome inhibitor bortezomib (formerly known as PS-341) triggers significant antitumor activity in multiple myeloma (MM) in both preclinical models and patients with relapsed refractory disease. Recent studies have shown that unfolded and misfolded ubiquitinated proteins ar...
שמור ב:
| Main Authors: | , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
National Academy of Sciences
2005
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1150844/ https://ncbi.nlm.nih.gov/pubmed/15937109 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0503221102 |
| תגים: |
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