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Mechanism of Action of Proteasome Inhibitors and Deacetylase Inhibitors and the Biological Basis of Synergy in Multiple Myeloma

Novel agents, including the proteasome inhibitor bortezomib, have significantly improved the response and survival of patients with multiple myeloma (MM) over the last decade. Despite these advances, many patients relapse or do not benefit from the currently available therapies; thus, MM remains an...

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Dettagli Bibliografici
Pubblicato in:Mol Cancer Ther
Autori principali: Hideshima, Teru, Richardson, Paul G., Anderson, Kenneth C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5527560/
https://ncbi.nlm.nih.gov/pubmed/22072815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-11-0433
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