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The 2.2-Kilobase Latency-Associated Transcript of Herpes Simplex Virus Type 2 Does Not Modulate Viral Replication, Reactivation, or Establishment of Latency in Transgenic Mice

To better understand the mechanisms responsible for the observed effects of deletions in the promoter region of the latency-associated transcript (LAT) gene in impairing herpes simplex virus (HSV) reactivation, we generated mice transgenic for a 5.5-kb HSV type 2 (HSV-2) genomic fragment spanning th...

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Udgivet i:J Virol
Principais autores: Wang, Kening, Pesnicak, Lesley, Guancial, Elizabeth, Krause, Philip R., Straus, Stephen E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2001
Fag:
Pathogenesis and Immunity
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC115061/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11483762/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.17.8166-8172.2001
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