The 2.2-Kilobase Latency-Associated Transcript of Herpes Simplex Virus Type 2 Does Not Modulate Viral Replication, Reactivation, or Establishment of Latency in Transgenic Mice

To better understand the mechanisms responsible for the observed effects of deletions in the promoter region of the latency-associated transcript (LAT) gene in impairing herpes simplex virus (HSV) reactivation, we generated mice transgenic for a 5.5-kb HSV type 2 (HSV-2) genomic fragment spanning th...

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הוצא לאור ב:	J Virol
Principais autores:	Wang, Kening, Pesnicak, Lesley, Guancial, Elizabeth, Krause, Philip R., Straus, Stephen E.
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	American Society for Microbiology (ASM) 2001
נושאים:	Pathogenesis and Immunity
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC115061/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11483762/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.17.8166-8172.2001
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