The 2.2-Kilobase Latency-Associated Transcript of Herpes Simplex Virus Type 2 Does Not Modulate Viral Replication, Reactivation, or Establishment of Latency in Transgenic Mice

To better understand the mechanisms responsible for the observed effects of deletions in the promoter region of the latency-associated transcript (LAT) gene in impairing herpes simplex virus (HSV) reactivation, we generated mice transgenic for a 5.5-kb HSV type 2 (HSV-2) genomic fragment spanning th...

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Detalhes bibliográficos
Main Authors: Wang, Kening, Pesnicak, Lesley, Guancial, Elizabeth, Krause, Philip R., Straus, Stephen E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC115061/
https://ncbi.nlm.nih.gov/pubmed/11483762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.17.8166-8172.2001
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