Varicella-Zoster Virus ORF47 Protein Kinase, Which Is Required for Replication in Human T Cells, and ORF66 Protein Kinase, Which Is Expressed during Latency, Are Dispensable for Establishment of Latency

Varicella-zoster virus (VZV) results in a lifelong latent infection in human sensory and cranial nerve ganglia after primary infection. VZV open reading frame 47 (ORF47) and ORF66 encode protein kinases that phosphorylate several viral proteins, including VZV glycoprotein gE and ORF32, ORF62, and OR...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Sato, Hitoshi, Pesnicak, Lesley, Cohen, Jeffrey I.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2003
Assuntos:	Pathogenesis and Immunity
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC225004/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14512565/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.20.11180-11185.2003
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