Varicella-Zoster Virus ORF47 Protein Kinase, Which Is Required for Replication in Human T Cells, and ORF66 Protein Kinase, Which Is Expressed during Latency, Are Dispensable for Establishment of Latency

Varicella-zoster virus (VZV) results in a lifelong latent infection in human sensory and cranial nerve ganglia after primary infection. VZV open reading frame 47 (ORF47) and ORF66 encode protein kinases that phosphorylate several viral proteins, including VZV glycoprotein gE and ORF32, ORF62, and OR...

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Bibliographic Details

Published in:	J Virol
Main Authors:	Sato, Hitoshi, Pesnicak, Lesley, Cohen, Jeffrey I.
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 2003
Subjects:	Pathogenesis and Immunity
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC225004/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14512565/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.20.11180-11185.2003
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