Degradation of the Retinoblastoma Tumor Suppressor by the Human Papillomavirus Type 16 E7 Oncoprotein Is Important for Functional Inactivation and Is Separable from Proteasomal Degradation of E7

The steady-state level and metabolic half-life of retinoblastoma tumor suppressor protein pRB are decreased in cells that express high-risk human papillomavirus (HPV) E7 proteins. Here we show that pRB degradation is a direct activity of E7 and does not reflect a property of cell lines acquired duri...

詳細記述

書誌詳細

出版年:	J Virol
主要な著者:	Gonzalez, Sonia L., Stremlau, Matt, He, Xi, Basile, John R., Münger, Karl
フォーマット:	Artigo
言語:	Inglês
出版事項:	American Society for Microbiology (ASM) 2001
主題:	Transformation and Oncogenesis
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114993/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11462030/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.16.7583-7591.2001
タグ:	タグ追加 タグなし, このレコードへの初めてのタグを付けませんか!