Protection against Simian Immunodeficiency Virus Vaginal Challenge by Using Sabin Poliovirus Vectors

Here we provide the first report of protection against a vaginal challenge with a highly virulent simian immunodeficiency virus (SIV) by using a vaccine vector. New poliovirus vectors based on Sabin 1 and 2 vaccine strain viruses were constructed, and these vectors were used to generate a series of...

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Autors principals: Crotty, Shane, Miller, Christopher J., Lohman, Barbara L., Neagu, Martha R., Compton, Lara, Lu, Ding, Lü, Fabien X.-S., Fritts, Linda, Lifson, Jeffrey D., Andino, Raul
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2001
Matèries:
Vaccines and Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC114979/
https://ncbi.nlm.nih.gov/pubmed/11462016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.16.7435-7452.2001
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