Incomplete Protection against Simian Immunodeficiency Virus Vaginal Transmission in Rhesus Macaques by a Topical Antiviral Agent Revealed by Repeat Challenges

The rising prevalence of human immunodeficiency virus type 1 (HIV-1) infection in women, especially in resource-limited settings, accentuates the need for accessible, inexpensive, and female-controlled preexposure prophylaxis strategies to prevent mucosal transmission of the virus. While many compou...

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Detalhes bibliográficos
Main Authors: Ambrose, Zandrea, Compton, Lara, Piatak, Michael, Lu, Ding, Alvord, W. Gregory, Lubomirski, Mariusz S., Hildreth, James E. K., Lifson, Jeffrey D., Miller, Christopher J., KewalRamani, Vineet N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2447098/
https://ncbi.nlm.nih.gov/pubmed/18434406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02730-07
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