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Mucosal Immunization of Cynomolgus Macaques with Two Serotypes of Live Poliovirus Vectors Expressing Simian Immunodeficiency Virus Antigens: Stimulation of Humoral, Mucosal, and Cellular Immunity

Poliovirus live virus vectors are a candidate recombinant vaccine system. Previous studies using this system showed that a live poliovirus vector expressing a foreign antigen between the structural and nonstructural proteins generates both antibody and cytotoxic T-lymphocyte responses in mice. Here...

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Detalhes bibliográficos
Main Authors: Crotty, Shane, Lohman, Barbara L., Lü, Fabien X.-S., Tang, ShenBei, Miller, Christopher J., Andino, Raul
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC112983/
https://ncbi.nlm.nih.gov/pubmed/10516057
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