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Two Overlapping Subdominant Epitopes Identified by DNA Immunization Induce Protective CD8(+) T-Cell Populations with Differing Cytolytic Activities
Subdominant CD8(+) T-cell responses contribute to control of several viral infections and to vaccine-induced immunity. Here, using the lymphocytic choriomeningitis virus model, we demonstrate that subdominant epitopes can be more reliably identified by DNA immunization than by other methods, permitt...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2001
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC114975/ https://ncbi.nlm.nih.gov/pubmed/11462012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.16.7399-7409.2001 |
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