CD4(+) T Cells Induced by a DNA Vaccine: Immunological Consequences of Epitope-Specific Lysosomal Targeting

Our previous studies have shown that targeting DNA vaccine-encoded major histocompatibility complex class I epitopes to the proteasome enhanced CD8(+) T-cell induction and protection against lymphocytic choriomeningitis virus (LCMV) challenge. Here, we expand these studies to evaluate CD4(+) T-cell...

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Autori principali: Rodriguez, Fernando, Harkins, Stephanie, Redwine, Jeffrey M., de Pereda, Jose M., Whitton, J. Lindsay
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2001
Soggetti:
Pathogenesis and Immunity
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC114616/
https://ncbi.nlm.nih.gov/pubmed/11581410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.21.10421-10430.2001
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