Immunodominance in Virus-Induced CD8(+) T-Cell Responses Is Dramatically Modified by DNA Immunization and Is Regulated by Gamma Interferon

The phenomenon whereby the host immune system responds to only a few of the many possible epitopes in a foreign protein is termed immunodominance. Immunodominance occurs not only during microbial infection but also following vaccination, and clarification of the underlying mechanism may permit the r...

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Bibliographic Details
Main Authors: Rodriguez, Fernando, Harkins, Stephanie, Slifka, Mark K., Whitton, J. Lindsay
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC155093/
https://ncbi.nlm.nih.gov/pubmed/11932390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.9.4251-4259.2002
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