Immunodominance in Virus-Induced CD8(+) T-Cell Responses Is Dramatically Modified by DNA Immunization and Is Regulated by Gamma Interferon

The phenomenon whereby the host immune system responds to only a few of the many possible epitopes in a foreign protein is termed immunodominance. Immunodominance occurs not only during microbial infection but also following vaccination, and clarification of the underlying mechanism may permit the r...

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Pubblicato in:	J Virol
Autori principali:	Rodriguez, Fernando, Harkins, Stephanie, Slifka, Mark K., Whitton, J. Lindsay
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2002
Soggetti:	Pathogenesis and Immunity
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC155093/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11932390/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.9.4251-4259.2002
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