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CD4(+) T Cells Induced by a DNA Vaccine: Immunological Consequences of Epitope-Specific Lysosomal Targeting

Our previous studies have shown that targeting DNA vaccine-encoded major histocompatibility complex class I epitopes to the proteasome enhanced CD8(+) T-cell induction and protection against lymphocytic choriomeningitis virus (LCMV) challenge. Here, we expand these studies to evaluate CD4(+) T-cell...

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Udgivet i:J Virol
Principais autores: Rodriguez, Fernando, Harkins, Stephanie, Redwine, Jeffrey M., de Pereda, Jose M., Whitton, J. Lindsay
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2001
Fag:
Pathogenesis and Immunity
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114616/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11581410/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.21.10421-10430.2001
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