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Polyomavirus Small t Antigen Prevents Retinoic Acid-Induced Retinoblastoma Protein Hypophosphorylation and Redirects Retinoic Acid-Induced G(0) Arrest and Differentiation to Apoptosis
Polyomavirus small t antigen (ST) impedes late features of retinoic acid (RA)-induced HL-60 myeloid differentiation as well as growth arrest, causing apoptosis instead. HL-60 cells were stably transfected with ST. ST slowed the cell cycle, retarding G(2)/M in particular. Treated with RA, the ST tran...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC114935/ https://ncbi.nlm.nih.gov/pubmed/11333911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.11.5302-5314.2001 |
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