Novel Retinoic Acid Derivative Induces Differentiation and Growth Arrest in Neuroblastoma

INTRODUCTION: Retinoic acid (RA) is a differentiating agent utilized as maintenance therapy for high-risk neuroblastoma (NB), but associated toxicities limit its use. We have previously shown that a non-toxic, novel rexinoid, 9-cis-UAB30 (UAB30), decreased NB cell proliferation and in vivo tumor gro...

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Veröffentlicht in:J Pediatr Surg
Hauptverfasser: Marayati, Raoud, Williams, Adele P., Bownes, Laura V., Quinn, Colin H., Stewart, Jerry E., Mroczek-Musulman, Elizabeth, Atigadda, Venkatram R., Beierle, Elizabeth A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7299742/
https://ncbi.nlm.nih.gov/pubmed/32164984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpedsurg.2020.02.027
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