EZH2 inhibition decreases neuroblastoma proliferation and in vivo tumor growth

Investigation of the mechanisms responsible for aggressive neuroblastoma and its poor prognosis is critical to identify novel therapeutic targets and improve survival. Enhancer of Zeste Homolog 2 (EZH2) is known to play a key role in supporting the malignant phenotype in several cancer types and kno...

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Bibliographic Details
Published in:PLoS One
Main Authors: Bownes, Laura V., Williams, Adele P., Marayati, Raoud, Stafman, Laura L., Markert, Hooper, Quinn, Colin H., Wadhwani, Nikita, Aye, Jamie M., Stewart, Jerry E., Yoon, Karina J., Mroczek-Musulman, Elizabeth, Beierle, Elizabeth A.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2021
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7942994/
https://ncbi.nlm.nih.gov/pubmed/33690617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0246244
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