EZH2 inhibition decreases neuroblastoma proliferation and in vivo tumor growth

Investigation of the mechanisms responsible for aggressive neuroblastoma and its poor prognosis is critical to identify novel therapeutic targets and improve survival. Enhancer of Zeste Homolog 2 (EZH2) is known to play a key role in supporting the malignant phenotype in several cancer types and kno...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Bownes, Laura V., Williams, Adele P., Marayati, Raoud, Stafman, Laura L., Markert, Hooper, Quinn, Colin H., Wadhwani, Nikita, Aye, Jamie M., Stewart, Jerry E., Yoon, Karina J., Mroczek-Musulman, Elizabeth, Beierle, Elizabeth A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7942994/
https://ncbi.nlm.nih.gov/pubmed/33690617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0246244
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