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Role for Fgr and Numb in retinoic acid-induced differentiation and G0 arrest of non-APL AML cells

Retinoic acid (RA) is a fundamental regulator of cell cycle and cell differentiation. Using a leukemic patient-derived in vitro model of a non-APL AML, we previously found that RA evokes activation of a macromolecular signaling complex, a signalosome, built of numerous MAPK-pathway-related signaling...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Kazim, Noor, Yen, Andrew
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8202776/
https://ncbi.nlm.nih.gov/pubmed/34136084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27969
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