CCR5, CXCR4, and CD4 Are Clustered and Closely Apposed on Microvilli of Human Macrophages and T Cells

The chemokine receptors CCR5 and CXCR4 act synergistically with CD4 in an ordered multistep mechanism to allow the binding and entry of human immunodeficiency virus type 1 (HIV-1). The efficiency of such a coordinated mechanism depends on the spatial distribution of the participating molecules on th...

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Bibliografiska uppgifter

I publikationen:	J Virol
Huvudupphov:	Singer, Irwin I., Scott, Solomon, Kawka, Douglas W., Chin, Jayne, Daugherty, Bruce L., DeMartino, Julie A., DiSalvo, Jerry, Gould, Sandra L., Lineberger, Janet E., Malkowitz, Lorraine, Miller, Michael D., Mitnaul, Lyndon, Siciliano, Salvatore J., Staruch, Mary Jo, Williams, Hollis R., Zweerink, Hans J., Springer, Martin S.
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	American Society for Microbiology (ASM) 2001
Ämnen:	Virus-Cell Interactions
Länkar:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114869/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11264367/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.8.3779-3790.2001
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