CCR5, CXCR4, and CD4 Are Clustered and Closely Apposed on Microvilli of Human Macrophages and T Cells

The chemokine receptors CCR5 and CXCR4 act synergistically with CD4 in an ordered multistep mechanism to allow the binding and entry of human immunodeficiency virus type 1 (HIV-1). The efficiency of such a coordinated mechanism depends on the spatial distribution of the participating molecules on th...

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Detalhes bibliográficos
Main Authors: Singer, Irwin I., Scott, Solomon, Kawka, Douglas W., Chin, Jayne, Daugherty, Bruce L., DeMartino, Julie A., DiSalvo, Jerry, Gould, Sandra L., Lineberger, Janet E., Malkowitz, Lorraine, Miller, Michael D., Mitnaul, Lyndon, Siciliano, Salvatore J., Staruch, Mary Jo, Williams, Hollis R., Zweerink, Hans J., Springer, Martin S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114869/
https://ncbi.nlm.nih.gov/pubmed/11264367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.8.3779-3790.2001
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