Murine Coronavirus Spike Protein Determines the Ability of the Virus To Replicate in the Liver and Cause Hepatitis

Recombinant mouse hepatitis viruses (MHV) differing only in the spike gene, containing A59, MHV-4, and MHV-2 spike genes in the background of the A59 genome, were compared for their ability to replicate in the liver and induce hepatitis in weanling C57BL/6 mice infected with 500 PFU of each virus by...

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Publikašuvnnas:	J Virol
Váldodahkkit:	Navas, Sonia, Seo, Su-Hun, Chua, Ming Ming, Sarma, Jayasri Das, Lavi, Ehud, Hingley, Susan T., Weiss, Susan R.
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	American Society for Microbiology (ASM) 2001
Fáttát:	Pathogenesis and Immunity
Liŋkkat:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114828/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11160748/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.5.2452-2457.2001
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