Murine Coronavirus Spike Protein Determines the Ability of the Virus To Replicate in the Liver and Cause Hepatitis

Recombinant mouse hepatitis viruses (MHV) differing only in the spike gene, containing A59, MHV-4, and MHV-2 spike genes in the background of the A59 genome, were compared for their ability to replicate in the liver and induce hepatitis in weanling C57BL/6 mice infected with 500 PFU of each virus by...

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Bibliografische Detailangaben

Veröffentlicht in:	J Virol
Hauptverfasser:	Navas, Sonia, Seo, Su-Hun, Chua, Ming Ming, Sarma, Jayasri Das, Lavi, Ehud, Hingley, Susan T., Weiss, Susan R.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2001
Schlagworte:	Pathogenesis and Immunity
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114828/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11160748/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.5.2452-2457.2001
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