Partial Restoration of Replication of Simian Immunodeficiency Virus by Point Mutations in either the Dimerization Initiation Site (DIS) or Gag Region after Deletion Mutagenesis within the DIS

We used the simian immunodeficiency virus (SIV) molecular clone SIVmac239 to generate a deletion construct, termed SD2, in which we eliminated 22 nucleotides at positions +398 to +418 within the putative dimerization initiation site (DIS) stem. This SD2 deletion severely impaired viral replication,...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Guan, Yongjun, Diallo, Karidia, Detorio, Mervi, Whitney, James B., Liang, Chen, Wainberg, Mark A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2001
Materias:
Replication
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC114782/
https://ncbi.nlm.nih.gov/pubmed/11689677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.23.11920-11923.2001
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares