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Novel, Live Attenuated Simian Immunodeficiency Virus Constructs Containing Major Deletions in Leader RNA Sequences

We have constructed a series of simian immunodeficiency virus (SIV) mutants containing deletions within a 97-nucleotide (nt) region of the leader sequence. Deletions in this region markedly decreased the replication capacity in tissue culture, i.e., in both the C8166 and CEMx174 cell lines, as well...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Guan, Yongjun, Whitney, James B., Liang, Chen, Wainberg, Mark A.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2001
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC115902/
https://ncbi.nlm.nih.gov/pubmed/11222701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.6.2776-2785.2001
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