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Activation of Na+/H+ exchange in human platelets stimulated by thrombin and a phorbol ester.

We have investigated changes in cytoplasmic pH (pHi) in activated human platelets, using the fluorescent probe 2,7-biscarboxyethyl-5(6)-carboxyfluorescein. Stimulation of platelets by thrombin or 12-O-tetradecanoylphorbol 13-acetate increased pHi by about 0.11 pH unit above the resting value. This i...

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Detalhes bibliográficos
Main Authors: Siffert, W, Siffert, G, Scheid, P
Formato: Artigo
Idioma:Inglês
Publicado em: 1987
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1147557/
https://ncbi.nlm.nih.gov/pubmed/3566711
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