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Characterization of the activation of Na+/H+ exchange in lymphocytes by phorbol esters: change in cytoplasmic pH dependence of the antiport.

Phorbol 12-myristate 13-acetate and other phorbol esters induce an intracellular alkalinization in rat thymic lymphocytes. An extracellular acidification can be recorded concomitantly. This transmembrane H+ (equivalent) flux is dependent on external Na+ and is amiloride sensitive. Phorbol esters als...

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Bibliographic Details
Main Authors: Grinstein, S, Cohen, S, Goetz, J D, Rothstein, A, Gelfand, E W
Format: Artigo
Language:Inglês
Published: 1985
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC397275/
https://ncbi.nlm.nih.gov/pubmed/2983345
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