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Binuclear platinum (II)-terpyridine complexes. A new class of bifunctional DNA-intercalating agent.

A series of binuclear DNA-binding ligands was prepared by linking two (2,2':6',2"-terpyridine)platinum(II) moieties via alpha omega-dithiols of the type HS-[CH2]n-SH where n = 4-10. A monomeric analogue was also synthesized. Compounds were characterized by elemental analysis and elect...

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Detalhes bibliográficos
Main Authors: McFadyen, W D, Wakelin, L P, Roos, I A, Hillcoat, B L
Formato: Artigo
Idioma:Inglês
Publicado em: 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1147201/
https://ncbi.nlm.nih.gov/pubmed/3800959
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