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The interaction of DNA-targeted platinum phenanthridinium complexes with DNA.

Cisplatin analogues were synthesised that consisted of platinum(II) diamine complexes tethered via a polymethylene chain ( n = 3, 5, 8 and 10) to a phenanthridinium cation. Both chloro and iodo leaving groups were examined. DNA adduct formation was quantitatively analysed using a linear amplificatio...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Principais autores: Whittaker, J, McFadyen, W D, Wickham, G, Wakelin, L P, Murray, V
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147812/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9705500/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.17.3933
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