The interaction of DNA-targeted platinum phenanthridinium complexes with DNA.

Cisplatin analogues were synthesised that consisted of platinum(II) diamine complexes tethered via a polymethylene chain ( n = 3, 5, 8 and 10) to a phenanthridinium cation. Both chloro and iodo leaving groups were examined. DNA adduct formation was quantitatively analysed using a linear amplificatio...

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Detaylı Bibliyografya
Asıl Yazarlar: Whittaker, J, McFadyen, W D, Wickham, G, Wakelin, L P, Murray, V
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1998
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC147812/
https://ncbi.nlm.nih.gov/pubmed/9705500
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