Metallointercalation Reagents. 2-Hydroxyethanethiolato(2,2′,2″-terpyridine)-platinum(II) Monocation Binds Strongly to DNA By Intercalation

The red, cationic complex 2-hydroxy-ethanethiolato(2,2′,2″-terpyridine)platinum(II), [(terpy)-Pt(SCH(2)CH(2)OH)](+), binds strongly to DNA by a mechanism involving intercalation. By means of fluorescence spectroscopy, the platinum complex was shown to inhibit competitively the binding of the interca...

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Hlavní autoři: Jennette, K. W., Lippard, S. J., Vassiliades, G. A., Bauer, W. R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 1974
Témata:
Biological Sciences: Biochemistry
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC434279/
https://ncbi.nlm.nih.gov/pubmed/4530265
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