CD4-Independent Use of Rhesus CCR5 by Human Immunodeficiency Virus Type 2 Implicates an Electrostatic Interaction between the CCR5 N Terminus and the gp120 C4 Domain

Envelope glycoproteins (Envs) of human immunodeficiency virus type 2 (HIV-2) are frequently able to use chemokine receptors, CXCR4 or CCR5, in the absence of CD4. However, while these Envs are commonly dual-tropic, no isolate has been described to date that is CD4 independent on both CXCR4 and CCR5....

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Bibliografische Detailangaben

Veröffentlicht in:	J Virol
Hauptverfasser:	Lin, George, Lee, Benhur, Haggarty, Beth S., Doms, Robert W., Hoxie, James A.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2001
Schlagworte:	Virus-Cell Interactions
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114658/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11602718/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.22.10766-10778.2001
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