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mRNA Decay during Herpesvirus Infections: Interaction between a Putative Viral Nuclease and a Cellular Translation Factor

During lytic infections, the virion host shutoff (Vhs) protein (UL41) of herpes simplex virus destabilizes both host and viral mRNAs. By accelerating mRNA decay, it helps determine the levels and kinetics of viral and cellular gene expression. In vivo, Vhs shows a strong preference for mRNAs, as opp...

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書目詳細資料
Main Authors: Feng, Pinghui, Everly, David N., Read, G. Sullivan
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2001
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC114601/
https://ncbi.nlm.nih.gov/pubmed/11581395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.21.10272-10280.2001
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