Regression of Established Human Papillomavirus Type 16 (HPV-16) Immortalized Tumors In Vivo by Vaccinia Viruses Expressing Different Forms of HPV-16 E7 Correlates with Enhanced CD8(+) T-Cell Responses That Home to the Tumor Site

Using vaccinia virus as a live vector, we show that the expression of human papillomavirus type 16 (HPV-16) E7 fused to a nonhemolytic portion of the Listeria monocytogenes virulence factor, listeriolysin O (LLO), induces an immune response that causes the regression of established HPV-16 immortaliz...

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Detalhes bibliográficos
Main Authors: Lamikanra, Abigail, Pan, Zhen-Kun, Isaacs, Stuart N., Wu, Tzyy-Choou, Paterson, Yvonne
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Gene Therapy
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114536/
https://ncbi.nlm.nih.gov/pubmed/11559797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.20.9654-9664.2001
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