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Combined Transcriptome and Proteome Analysis of Immortalized Human Keratinocytes Expressing Human Papillomavirus 16 (HPV16) Oncogenes Reveals Novel Key Factors and Networks in HPV-Induced Carcinogenesis

Although the role of high-risk human papillomaviruses (hrHPVs) as etiological agents in cancer development has been intensively studied during the last decades, there is still the necessity of understanding the impact of the HPV E6 and E7 oncogenes on host cells, ultimately leading to malignant tran...

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Détails bibliographiques
Publié dans:mSphere
Auteurs principaux: Yang, Ruwen, Klimentová, Jana, Göckel-Krzikalla, Elke, Ly, Regina, Gmelin, Nadine, Hotz-Wagenblatt, Agnes, Řehulková, Helena, Stulík, Jiří, Rösl, Frank, Niebler, Martina
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6437273/
https://ncbi.nlm.nih.gov/pubmed/30918060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00129-19
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