HPV16 RNA-LPX vaccine mediates complete regression of aggressively growing HPV-positive mouse tumors and establishes protective T cell memory

HPV16 infections are associated with a variety of cancers and there is compelling evidence that the transforming activity of HPV16 critically depends on the expression of the viral oncoproteins E6 and E7. Therapeutic cancer vaccines capable of generating durable and specific immunity against these H...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Grunwitz, Christian, Salomon, Nadja, Vascotto, Fulvia, Selmi, Abderaouf, Bukur, Thomas, Diken, Mustafa, Kreiter, Sebastian, Türeci, Özlem, Sahin, Ugur
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6685602/
https://ncbi.nlm.nih.gov/pubmed/31428528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2019.1629259
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