Improvement of In Vivo Expression of Genes Delivered by Self-Amplifying RNA Using Vaccinia Virus Immune Evasion Proteins

Among nucleic acid–based delivery platforms, self-amplifying RNA (saRNA) vectors are of increasing interest for applications such as transient expression of recombinant proteins and vaccination. saRNA is safe and, due to its capability to amplify intracellularly, high protein levels can be produced...

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Detalhes bibliográficos
Publicado no:Hum Gene Ther
Main Authors: Beissert, Tim, Koste, Lars, Perkovic, Mario, Walzer, Kerstin C., Erbar, Stephanie, Selmi, Abderraouf, Diken, Mustafa, Kreiter, Sebastian, Türeci, Özlem, Sahin, Ugur
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2017
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Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737720/
https://ncbi.nlm.nih.gov/pubmed/28877647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2017.121
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