Identification and Characterization of a Peptide That Specifically Binds the Human, Broadly Neutralizing Anti-Human Immunodeficiency Virus Type 1 Antibody b12

Human monoclonal antibody (MAb) b12 recognizes a conformational epitope that overlaps the CD-4-binding site of the human immunodeficiency virus type 1 (HIV-1) envelope. MAb b12 neutralizes a broad range of HIV-1 primary isolates and protects against primary virus challenge in animal models. We repor...

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Detalhes bibliográficos
Main Authors: Zwick, Michael B., Bonnycastle, Lori L. C., Menendez, Alfredo, Irving, Melita B., Barbas, Carlos F., Parren, Paul W. H. I., Burton, Dennis R., Scott, Jamie K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114393/
https://ncbi.nlm.nih.gov/pubmed/11413337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.14.6692-6699.2001
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