Hepatitis C Virus E2-CD81 Interaction Induces Hypermutation of the Immunoglobulin Gene in B Cells

Hepatitis C virus (HCV) is one of the leading causes of chronic liver diseases and B-lymphocyte proliferative disorders, including mixed cryoglobulinemia and B-cell lymphoma. It has been suggested that HCV infects human cells through the interaction of its envelope glycoprotein E2 with a tetraspanin...

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Detalhes bibliográficos
Main Authors: Machida, Keigo, Cheng, Kevin T.-H., Pavio, Nicole, Sung, Vicky M.-H., Lai, Michael M. C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1143751/
https://ncbi.nlm.nih.gov/pubmed/15956553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.13.8079-8089.2005
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