Hepatitis C Virus Infection Activates the Immunologic (Type II) Isoform of Nitric Oxide Synthase and Thereby Enhances DNA Damage and Mutations of Cellular Genes

Hepatitis C virus (HCV) infection causes hepatitis, hepatocellular carcinoma, and B-cell lymphomas in a significant number of patients. Previously we have shown that HCV infection causes double-stranded DNA breaks and enhances the mutation frequency of cellular genes, including proto-oncogenes and i...

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Detalhes bibliográficos
Main Authors: Machida, Keigo, Cheng, Kevin T.-H., Sung, Vicky M.-H., Lee, Ki Jeong, Levine, Alexandra M., Lai, Michael M. C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC479064/
https://ncbi.nlm.nih.gov/pubmed/15280491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.16.8835-8843.2004
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